The 35-year-old Bryans, who also won the Olympic gold medal last year, got the measure of their 12th-seeded opponents through the telepathic understanding which has brought them 91 career doubles titles.
They made the decisive break in the ninth game of the fourth set and Bob Bryan served out for victory which he sealed with an ace, prompting a trademark chest-pump by the brothers.
The world number two, who also holds the US Open and Olympic titles, has quickly been installed as the 1/20 favourite to win the Sports Personality of the Year award but there is also speculation he could earn recognition in the New Year honours list.
While Cameron has no influence over what is an independent process, the Conservative Prime Minster believes Murray is deserving of being knighted, saying on Monday: "Frankly, I can't think of anyone who deserves one more.”
Cameron, who watched Murray’s victory from the royal box at Wimbledon, added that the moment of sporting glory "lifted the spirits of the whole country".
He added: "It was a fantastic day for Andy Murray, for British tennis and for Britain … We were wondering yesterday morning, 'Do we dare to dream that this is possible?' and he proved absolutely that it was."
He came out to serve for the title as a far from reserved roar, an unleashing of national frustration after so many years, reverberated around the hallowed Centre Court.
Murray quickly established three Championship points and then squandered them all.
He then saved three break points before producing a brilliant winner to set up another chance, which he finally took to end Britain's 77-year wait for a men's singles winner.
The British number one now holds the Olympic, US Open and Wimbledon titles - and, at just 26, is still at the peak of his powers meaning there is surely more to come.
"Winning Wimbledon is the pinnacle of tennis. Those last few points were the hardest of my life and I worked so hard in that last game," said Murray.
"I just can't get my head around it, I can't quite believe it.
"It's all a bit of a blur, from 4-2 down in the third set to holding the trophy, I don't know what to say.
"Mentally, that last game was the toughest game I will play in my entire career. I can't really believe that it's happened. This one will take a while to sink in."
Murray paid special tribute to coach Ivan Lendl, himself a two-time beaten finalist at Wimbledon, who has perhaps added a decisive missing ingredient to the world number two's entourage since his appointment early last year.
"He told me he was proud of me, which coming from him means a lot," added Murray.
"He doesn't smile too much in public but away from the cameras and crowds he is a very different character.
"He'd have loved to win here but this was the next best thing for him, he's stuck by me through some tough losses, he's been very patient and I'm happy I managed to do it for him.
"Ivan has made me learn more from my losses. He is extremely honest with me, if I work hard then he is happy. If I don't, he's disappointed and will tell me.
"He's got my mentality slightly different heading into these big matches."
Murray also paid tribute to the crowd - normally the most reserved on the Grand Slam circuit - who waved their flags and raised the roof with the sort of chanting you normally only find at the Davis Cup.
"It was a different atmosphere to the past, it was incredibly loud," he said.
"It does make a difference and it really helps when the crowd is like that. It's especially good in a tough matches, when it's extremely hot and there are long, brutal rallies. It helps get you through."
Murray admits to feeling strange that his entire career has been contrasted with a player, Fred Perry, who died when he was just seven years old.
And he hopes that he won't be held up as a similar example for those that will surely be inspired by his Wimbledon victory.
"It's an incredibly difficult tournament to win, so it's possible it could take a long time but I would hope not that long," said Murray.
"I think with the amount of money that is invested in the sport in this country, then it shouldn't take 70 odd years."
Her 6-1 6-4 victory over Germany's Sabine Lisicki completed a remarkable journey for the 28-year-old and finally vindicated her father's faith in doing things his way.
"I'm no tennis player so maybe my ideas were completely new, that's why a long time ago I was disturbing everybody," Walter, who introduced his daughter to tennis aged six after studying the style of Monica Seles, told reporters on a sun-splashed balcony alongside Centre Court.
"The tennis players thought this guy is crazy, these ideas are completely stupid but I kept believing in myself and Marion and me found our way to do things."
Bartoli has been consistently in the top 20 of the WTA rankings for six years but after a difficult season in which she had not gone past the quarter-finals at any tournament she was well down the list of potential Wimbledon winners.
She even stopped being coached by dad, working instead with former Wimbledon champion Amelie Mauresmo, but she sought him out for a warm embrace after firing down an ace to claim the title.
After some worrying time when she says she hit "rock bottom" everything finally fell into place - the ultimate reward for daring to be a little different.
"That's always been a part of my personality to be different," she told a new conference. "I think being just like the other one is kind of boring.
"At the end of the day, when the spectators were looking at 10 matches they will remember this girl that was doing something different, playing inside the court or whatever."
"It was the perfect day. It was sunny. It was beautiful. Centre Court Wimbledon, it was packed," added Bartoli, the first French player to win a slam since Mauresmo in 2006.
"I won in two sets. I didn't drop a set for the whole championship. Even in my perfect dream I couldn't have dreamed a perfect moment like that. That is beyond perfection."
Bartoli's style is based on taking the ball extremely early and being aggressive on every ball.
Those early days when she learnt her strokes on an indoor court with no space behind the baselines are still evident because the Frenchwoman always moves forward.
So is the intense focus that became an ingrained habit thanks to Walter's novel use of different coloured tennis balls, "some very speedy, some very low" he explains of one of the various unconventional coaching methods he introduced.
Sometimes she stands two metres inside the baseline to receive serve - a skill that requires incredible hand-eye coordination and Walter made use of video to study the way balls bounce.
The perpetual motion mannerisms, the imaginary swings behind the baseline, the running on the spot, the fist-pumps, are also key to the Bartoli blueprint.
"I told her to be a good player you have to have a routine and stick with it," said Walter, a doctor by profession. "The thing is for her not to be passive on the court. With her (double-fisted style) it's very difficult to come back in a rally, that's why she wins lots of quick rallies."
There have been "pain and tears" during her journey and heartache too when she missed the Olympics because of her decision not to play Fed Cup in protest at her father not being allowed to work with the team.
All that was forgotten on Saturday, even if Walter never imagined his daughter could one day be a Grand Slam champion.
"For sure I was thinking that she was a talented player and can have some fun on the tennis court and that's all," he said.
"She asked to be a champion and I helped her to be one. She used to say dad I want to improve my serve, have more speed, and I'd find each time a new exercise."
Peng is the third Chinese to win a Grand Slam doubles title.
It was the third time Dellacqua finished runner-up in a women's doubles final at a Grand Slam. However, she did win the 2011 French Open mixed doubles title with American Scott Lipsky.
However Judy, who is coach of the British Fed Cup team, told the BBC’s Newsnight programme that she fears the wave of optimism will break under a lack of facilities at grassroots level.
"The country will go tennis crazy. Kids and adults will want to try tennis and not all of them will get the opportunity," she said.
"The key is to make sure there are as many public courts in as many communities we can put them in if we're going to tap into this great imagination…
"I'd like it to become way more inclusive. I think it still is [too elitist]. Some moves have been made to make things better but there's still such a long way to go and there are huge swathes of the country where you can't find tennis courts.
"You need to build courts in areas where they currently don't exist for it to become a much more inclusive sport…
"We need to get into rural areas and disadvantaged areas and get tennis to people that haven't had the opportunity to play.”
However Tom Gibbins, head of education at the Lawn Tennis Association, refuted the notion that tennis is inaccessible.
"We're trying to dispel lots of myths about tennis and one is that it has to be an expensive sport to play. The average weekly membership of a tennis club is less than £1.50 a week for a junior to play,” he told BBC London.
"Andy gave British tennis its greatest moment ever and it's our job to capitalise on that interest and inspire more kids and adults to play tennis.
"There are 20,000 tennis courts up and down the country, 1,500 of which are free. Tennis isn't an expensive sport especially at beginner and recreational level."
Ivo Karlovic has stated that he didn’t ‘know his name’ or ‘what year it was’ as he recovers from viral meningitis.
The 6’ 10” Croatian, who makes his long-awaited return to the tour in the Hall of Fame Tennis Championships on Friday, says that he now feels lucky to even be competing again after doctors stated that they weren’t sure whether he would ever fully recover.
The 34-year-old was preparing for an event on the Challenger Tour in April when the symptoms first occurred.
“I woke up and my arm was numb,” Karlovic recalled. “Then my wife [Alsi] asked me I don’t even remember what. I was slurring, so she called the paramedics.
“They gave me IV [therapy] and I felt good. But when they left, I began to vomit a lot and had headaches, so I went to hospital.
“They released me after one hour, but later that evening the numbness and pain returned. I became less and less conscious. I returned to hospital again. I don’t know what happened after that.”
“The doctor’s didn’t really know if I would recover 100 per cent. I was unconscious for a long time. I didn’t know my name or what year it was. I was in a lot of pain. My right arm and my face was numb.
“Headaches lasted almost 10 days. I recalled my name after four days and the numbness disappeared after five days.”
After making a recover from the illness, Karlovic has since struggled getting back to full match-fitness.
“The toughest part was fitness, and the fact that I didn’t know if it would happen again because there was still a virus in my head,” he added.
“I took to the practice court after one month. Five minutes one week and then every day. I really didn’t know that I would be back, so now it is good feeling because I feel no stress.
“It’s like a bonus. Every day now that I’m actually in a match, the atmosphere is like a bonus. I really like it now a lot more.
“I’m not fearful any more. The goal is just to be healthy and here. So it’s fun.”
She sobbed on court during her second set meltdown but recovered her composure in time to face the world's media.
"I felt fine this morning but it's an occasion that you don't get every day," she told a news conference. "So it's something completely new for me.
"The walk on court is different. You walk on with the flowers. You walk on together. Everything is a little bit different. The feeling, the atmosphere is different."
Lisicki beat defending champion Serena Williams and last year's runner-up Agnieszka Radwanska on the way to the final and, on her favourite surface, was favourite to beat the 15th-seeded Bartoli.
But she was never able to produce consistently the booming serves and thumping forehands which took her to the final and made a string of costly unforced errors.
"I will learn and take away so much from it," Lisicki, seeded 23rd, said after her first Wimbledon final, having reached the semi-final in 2011.
"I've done that in the past. Experience has always helped me so much.
"When I was in the quarters here the first time, when I was in the semis for the first time, and now in the final for the first time. I've always gained my experience here, which is good.
"I hope that next time it will help me to do that one step further."
Lisicki, 23, agreed that the 28-year-old Bartoli, who did not drop a set in the tournament, had more energy left for the final after an easier run.
"Having so many hard matches is draining in the end of the day. I think Marion was fresher today. I think that made a big difference too," she said.
Lisicki was taking plenty of positives from her performances at Wimbledon.
"It's still been a great tournament," she said. "It's been an amazing two weeks.
"I've played my best tennis here. I had to take out the champion and runner-up from last year, so I think that's pretty big. This tournament definitely made me a better player."
Murray won last year’s US Open to end what was then a 76-year wait for a British male Grand Slam champion; he is now the first Briton of either gender to win Wimbledon since Virginia Wade in 1977, and the first male since Fred Perry in 1936.
"It feels slightly different to last year," Murray said in reference to his tearful defeat in the 2012 final. "I don't know how I managed to get through that last game - losing three match points was unbelievable. It was hard to watch but imagine playing it!
"Novak has come back so many times from similar positions and he almost did it again."
The beaten world number one was typically sportsmanlike at the trophy presentation.
"Congratulations to Andy, who absolutely deserved this win - you played incredible tennis," Djokovic said. "I know how much it means to all of you guys, the whole country, well done.
"I'm aware of the pressure he gets, although I cannot imagine the extent not being in his shoes.
"It was an absolute pleasure and an honour to be part of this final."
Murray was exceptional at times but, by contrast, Djokovic had one of his worst games on Centre Court.
On the hottest day of the year in Britain, with the mercury soaring toward 30 degrees Celsius, the world's two best players produced some scorching sinew-stretching action from the start and the first three games alone lasted 20 minutes.
The opening salvo of the Centre Court clash lasted 20 strokes as Murray went up 0-40 on the Serb's serve but Djokovic produced staunch defence to stave off his opponent's attack.
The duo did trade breaks in the third and fourth games, with each Murray winner being greeted by a chorus of 15,000 roars.
Second seed Murray got another chance to break to love in the seventh game and this time he pounced as the 2011 champion surrendered his serve by slapping a backhand into the net.
A set that initially looked like lasting forever ended exactly on the hour mark as Djokovic whipped a service return wide to give Murray, runner-up to Roger Federer last year, the one-set cushion.
The battle between the two players who were born seven days apart in 1987 intensified in the second set as they went toe-to-toe from the baseline with 25-shot rallies being par for the course.
Djokovic, who survived a four hour 43 minute semi-final epic against Juan Martin Del Potro two days ago, showed his super-human ability to recover quickly as he ran down everything Murray could throw at him.
The Serb rattled Murray by going for the lines and broke for a 3-1 lead when Olympic champion Murray flicked a forehand into the net.
Even when Djokovic slipped and skidded flat on to his stomach while trying to chase down a Murray winner, the six-times Grand Slam champion appeared unfazed as he quickly got back on to his feet to extend his lead to 4-1.
But Murray, who trains in the intense Miami heat, showed off his iron-man conditioning as he stormed back to level at 4-4, a Djokovic double fault on break point down handing him the break back in the seventh game.
While the cheering crowd, which included British Prime Minister David Cameron, got behind a pumped up Murray, Djokovic simply exploded in anger in the 11th game.
Convinced that Murray had gone long mid-rally at 15-15, he screamed at umpire Mohamed Lahyani "Why? What's going on?" as he gesticulated wildly to show what he thought the linesman had failed to see.
Murray ignored the uproar to break the fuming Serb and soon had the fans roaring when he wrapped up the 69-minute second set with a 125mph thunderbolt ace.
The third set initially seemed a formality for Murray, who broke Djokovic early and almost sealed a double-break.
But two sloppy drop shots allowed the Serb to break back, with a rejuvenated Djokovic holding before winning the subsequent Murray service game as the Briton seemed to lose momentum.
Murray, however, has incredible mental and physical reserves and cancelled out that break with some intense hustling at the net, bringing it back with serve, which he held with a wonderful diving forehand off the baseline.
That was followed by a magnificent break for Murray, which boasted two astounding last-gasp winners, leaving him serving for the title.
Initially Djokovic saved three championship points as a nervy Murray’s serve deserted him, and the Serb even had three break-back points thanks to an unforced error to net from the Briton, a wonderful drop-shot off the net-cord and then a beautiful diving winner across the net.
But Murray saved them all, bringing up his fourth match point with some incredible fight at the baseline, his forehand pass forcing Djokovic to net a volley.
And, after his next serve was returned just inside the baseline, Murray was a spectator as Djokovic netted the follow up, sending Centre Court and an entire nation into raptures.
Murray, who took the first set 6-4, came from a break down to clinch the second, breaking Djokovic's serve again at 5-5 before holding to love.
The world number two would be the first British male to win the Wimbledon title in 77 years.
Murray won his first Grand Slam title at the US Open last year.
Murray won last year’s US Open to end what was then a 76-year wait for a British male Grand Slam champion; he is now the first Briton of either gender to win Wimbledon since Virginia Wade in 1977, and the first male since Fred Perry in 1936.
"It feels slightly different to last year," Murray said in reference to his tearful defeat in the 2012 final. "I don't know how I managed to get through that last game - losing three match points was unbelievable. It was hard to watch but imagine playing it!
"Novak has come back so many times from similar positions and he almost did it again."
The beaten world number one was typically sportsmanlike at the trophy presentation.
"Congratulations to Andy, who absolutely deserved this win - you played incredible tennis," Djokovic said. "I know how much it means to all of you guys, the whole country, well done.
"I'm aware of the pressure he gets, although I cannot imagine the extent not being in his shoes.
"It was an absolute pleasure and an honour to be part of this final."
Murray was exceptional at times but, by contrast, Djokovic had one of his worst games on Centre Court.
On the hottest day of the year in Britain, with the mercury soaring toward 30 degrees Celsius, the world's two best players produced some scorching sinew-stretching action from the start and the first three games alone lasted 20 minutes.
The opening salvo of the Centre Court clash lasted 20 strokes as Murray went up 0-40 on the Serb's serve but Djokovic produced staunch defence to stave off his opponent's attack.
The duo did trade breaks in the third and fourth games, with each Murray winner being greeted by a chorus of 15,000 roars.
Second seed Murray got another chance to break to love in the seventh game and this time he pounced as the 2011 champion surrendered his serve by slapping a backhand into the net.
A set that initially looked like lasting forever ended exactly on the hour mark as Djokovic whipped a service return wide to give Murray, runner-up to Roger Federer last year, the one-set cushion.
The battle between the two players who were born seven days apart in 1987 intensified in the second set as they went toe-to-toe from the baseline with 25-shot rallies being par for the course.
Djokovic, who survived a four hour 43 minute semi-final epic against Juan Martin Del Potro two days ago, showed his super-human ability to recover quickly as he ran down everything Murray could throw at him.
The Serb rattled Murray by going for the lines and broke for a 3-1 lead when Olympic champion Murray flicked a forehand into the net.
Even when Djokovic slipped and skidded flat on to his stomach while trying to chase down a Murray winner, the six-times Grand Slam champion appeared unfazed as he quickly got back on to his feet to extend his lead to 4-1.
But Murray, who trains in the intense Miami heat, showed off his iron-man conditioning as he stormed back to level at 4-4, a Djokovic double fault on break point down handing him the break back in the seventh game.
While the cheering crowd, which included British Prime Minister David Cameron, got behind a pumped up Murray, Djokovic simply exploded in anger in the 11th game.
Convinced that Murray had gone long mid-rally at 15-15, he screamed at umpire Mohamed Lahyani "Why? What's going on?" as he gesticulated wildly to show what he thought the linesman had failed to see.
Murray ignored the uproar to break the fuming Serb and soon had the fans roaring when he wrapped up the 69-minute second set with a 125mph thunderbolt ace.
The third set initially seemed a formality for Murray, who broke Djokovic early and almost sealed a double-break.
But two sloppy drop shots allowed the Serb to break back, with a rejuvenated Djokovic holding before winning the subsequent Murray service game as the Briton seemed to lose momentum.
Murray, however, has incredible mental and physical reserves and cancelled out that break with some intense hustling at the net, bringing it back with serve, which he held with a wonderful diving forehand off the baseline.
That was followed by a magnificent break for Murray, which boasted two astounding last-gasp winners, leaving him serving for the title.
Initially Djokovic saved three championship points as a nervy Murray’s serve deserted him, and the Serb even had three break-back points thanks to an unforced error to net from the Briton, a wonderful drop-shot off the net-cord and then a beautiful diving winner across the net.
But Murray saved them all, bringing up his fourth match point with some incredible fight at the baseline, his forehand pass forcing Djokovic to net a volley.
And, after his next serve was returned just inside the baseline, Murray was a spectator as Djokovic netted the follow up, sending Centre Court and an entire nation into raptures.
MURRAY 2-2 DJOKOVIC: Murray finally converts his eighth break point of the match to take a 2-1 lead, but the Serbian immediately hits back to level the set.
MURRAY 4-3 DJOKOVIC: Undaunted, Murray races to 0-40 on the Djokovic serve and the number one seed nets a backhand to the delight of the home crowd - it proves crucial as Murray goes on to win the first set 6-4.
MURRAY 6-4 1-3 DJOKOVIC: The expected Djokovic response arrives, as he sets up two break points after a 30-shot rally before converting to take the edge in the second set.
MURRAY 6-4 3-4 DJOKOVIC: An uncharacteristically sloppy game from the Serb, who gives away his serve with a double fault and the momentum shifts back to Briton's way.
MURRAY 6-4 6-5 DJOKOVIC: Controversy as Djokovic tries to challenge a call, only to be told he has none remaining - the replay shows Murray's shot was in anyway, but an unsettled Serb gifts his serve away again, allowing Murray to claim the second set 7-5.
MURRAY 6-4 7-5 1-0 DJOKOVIC: The finish line is in sight as Murray, on a run of eight games out of nine, breaks yet again - he clinches the game via a successful challenge when Djokovic slices a backhand long.
MURRAY 6-4 7-5 2-4 DJOKOVIC: But hold on a minute! Murray's level drops at the same time as his opponent steps it up, and consecutive breaks of serve appear to put Djokovic in total command of the third.
MURRAY 6-4 7-5 3-4 DJOKOVIC: Another twist, as Murray finds inspiration and turns the tide, and a delirious centre court crowd roar him on to another break and parity in the third set.
MURRAY 6-4 7-5 5-4 DJOKOVIC: Surely not? Andy Murray will serve for the Wimbledon title after a game of thrilling brilliance, including an astonishing forehand pass on the run.
MURRAY 6-4 7-5 6-4 DJOKOVIC: Murray races into a 40-0 lead before passing up three championship points, then saving tewo break back points amid heart-stopping drama. Djokovic eventually nets and Murray sinks to his knees.
Wimbledon singles champion Marion Bartoli, a close friend of Mladenovic's, watched the match from the stands before heading off for the champions ball.
It was the 40-year-old Nestor's third grand slam mixed doubles title and he has also won eight major men's doubles crowns, including two at the All England Club, and the 2000 Olympic gold medal.
The 39-year-old Raymond has won four grand slam titles in women's doubles and seven in mixed, including last year's crown at Wimbledon in partnership with compatriot Mike Bryan who won the men's doubles title with his brother Bob on Saturday.
The Russian said Hogstedt was “not able to travel in the near future”, and two days later the 26-year-old made public her new coach will be the 60-year-old Connors via her official website.
"I am really excited about our new partnership and looking forward to the upcoming tournaments," she said.
"After almost three years of working together, Thomas Hogstedt and I decided to part ways.
"I am very thankful for all his work, and wish him much success in the future."
Connors won five US Open men’s singles titles, as well as Wimbledon twice and one Australian Open, and topped the ATP rankings from July 1974 to August 1977.
Connors has worked with Sharapova in the past, during her preparations for the Australian Open in 2008.
